Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

HEAL-116

HEAL-116 is a potent, specific and orally active 3β-hydroxysteroid dehydrogenase type 1 (3βHSD1) inhibitor with an IC50 of 1.18 μM and a KD of 1.32 μM. HEAL-116 inhibits DHEA metabolism and DHEA-induced target gene expression and cell proliferation. HEAL-116 can be used for cancer research, such as prostate cancer[1].

Product Specifications

CAS Number

3059767-85-7

UNSPSC

12352100

Target

3β-HSD

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

OC1=CC(OC=C(C2=CC=C(Cl)C(CN3CCOCC3)=C2)C4=O)=C4C=C1

Molecular Formula

C20H18ClNO4

Molecular Weight

371.81

References & Citations

[1]He D, et al. Fine structural design of 3βHSD1 inhibitors for prostate cancer therapy. Proc Natl Acad Sci U S A. 2025 Jul;122 (26) :e2422267122.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

3β-HSD I

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Rabbit Polyclonal actin-related protein 2/3 complex subunit 1B Antibody [Alexa Fluor 350]
NBP2-97184AF350 0.1 mL

Rabbit Polyclonal actin-related protein 2/3 complex subunit 1B Antibody [Alexa Fluor 350]

Sign In for Pricing
View Details
Recombinant Shigella flexneri Flagellin (fliC), partial
MBS1375870-01 0.02 mg (E-Coli)

Recombinant Shigella flexneri Flagellin (fliC), partial

Sign In for Pricing
View Details
Recombinant Shigella flexneri Flagellin (fliC), partial
MBS1375870-02 0.1 mg (E-Coli)

Recombinant Shigella flexneri Flagellin (fliC), partial

Sign In for Pricing
View Details
Recombinant Shigella flexneri Flagellin (fliC), partial
MBS1375870-03 1 mg (E-Coli)

Recombinant Shigella flexneri Flagellin (fliC), partial

Sign In for Pricing
View Details
Recombinant Shigella flexneri Flagellin (fliC), partial
MBS1375870-04 5x 1 mg (E-Coli)

Recombinant Shigella flexneri Flagellin (fliC), partial

Sign In for Pricing
View Details
MAGBI Polyclonal Antibody
RA33213-01 50 µL

MAGBI Polyclonal Antibody

Sign In for Pricing
View Details