PI4K-IN-2

PI4K-IN-2 (Compound 30) is a highly selective type III phosphatidylinositol 4-kinase β (PI4KB) inhibitor (IC50=0.015 μM) . PI4K-IN-2 is promising for research of human rhinovirus (HRV) [1].

Product Specifications

CAS Number

[2411491-16-0]

UNSPSC

12352005

Target

Enterovirus; PI4K

Related Pathways

Anti-infection; PI3K/Akt/mTOR

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

CC(C)(C1=CN2C(C3=CC=C(C(S(=O)(N[C@H]4CC[C@H](CC4)O)=O)=C3)OC)=C(N=C2S1)C)C

Molecular Formula

C23H31N3O4S2

Molecular Weight

477.64

References & Citations

[1]Ochiai K, et al. Design and synthesis of imidazo[2,1-b]thiazole derivatives as potent and selective phosphatidylinositol 4-kinase IIIβ inhibitors for antiviral activity. Bioorg Med Chem Lett. 2025 Dec 1;128:130346.