CNV-dopamine

CNV-dopamine is a photoreleasable D2 receptor-selective agonist. CNV-dopamine activates D2 receptors and induces G protein-coupled inwardly rectifying potassium (GIRK) currents. CNV-dopamine is promising for research of disorders like Parkinson’s disease and addiction[1].

Product Specifications

UNSPSC

12352005

Target

Dopamine Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Smiles

OC1=CC(CCN)=CC=C1OC(C2=CC(OC)=C(C=C2[N+]([O-])=O)OC)C(O)=O.NCCC3=CC=C(C(OC(C4=CC(OC)=C(C=C4[N+]([O-])=O)OC)C(O)=O)=C3)O

Molecular Formula

C18H20N2O8

Molecular Weight

392.36

References & Citations

[1]Robinson BG, et al. Desensitized D2 autoreceptors are resistant to trafficking. Sci Rep. 2017 Jun 29;7 (1) :4379.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

D2 Receptor

Curated Selection

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