CYP1B1-IN-10
CYP1B1-IN-10 (Compound 15C) is a highly selective human cytochrome P450 1B1 (hCYP1B1) inhibitor (IC50=0.11 μM) . CYP1B1-IN-10 is promising for research of hormone-dependent tumors (e.g., breast and ovarian cancers) [1].
Product Specifications
CAS Number
[2785358-47-4]
UNSPSC
12352005
Target
Aryl Hydrocarbon Receptor; Cytochrome P450
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
CC1=CC(C2=NC(C=CC=C3)=C3CC4=C2NC5=C4C=CC=C5)=CC=C1
Molecular Formula
C23H18N2
Molecular Weight
322.40
References & Citations
[1]Wang J, et al. Discovery and synthesis of azepinoindoles as novel hCYP1B1 inhibitors with AhR-independent anticancer activity. Bioorg Chem. 2025 Aug;163:108786.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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