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CYP1B1-IN-10

CYP1B1-IN-10 (Compound 15C) is a highly selective human cytochrome P450 1B1 (hCYP1B1) inhibitor (IC50=0.11 μM) . CYP1B1-IN-10 is promising for research of hormone-dependent tumors (e.g., breast and ovarian cancers) [1].

Product Specifications

CAS Number

2785358-47-4

UNSPSC

12352005

Target

Aryl Hydrocarbon Receptor; Cytochrome P450

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

CC1=CC(C2=NC(C=CC=C3)=C3CC4=C2NC5=C4C=CC=C5)=CC=C1

Molecular Formula

C23H18N2

Molecular Weight

322.40

References & Citations

[1]Wang J, et al. Discovery and synthesis of azepinoindoles as novel hCYP1B1 inhibitors with AhR-independent anticancer activity. Bioorg Chem. 2025 Aug;163:108786.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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