BTK ligand 16
BTK ligand 16 is a BTK ligand that can be used for synthesis of TQ-3959.
Product Specifications
UNSPSC
12352005
Target
Btk; Ligands for Target Protein for PROTAC
Related Pathways
PROTAC; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
NC(C1=C(NC2=CC=C(C)C=C2)N=C(N3C[C@H](N4CCN(C)C4=O)CCC3)C=N1)=O
Molecular Formula
C21H27N7O2
Molecular Weight
409.48
References & Citations
[1]Ren J, et al. Discovery of TQ-3959 as a Potent and Orally Bioavailable BTK PROTAC Degrader Incorporating a Novel Benzisoxazole-Based CRBN Ligand for the Treatment of B-Cell Malignancies. J Med Chem. 2025 Aug 14;68 (15) :15960-15979.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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