DNA gyrase/Topo IV-IN-2
DNA gyrase/Topo IV-IN-2 (Compound AK19) is an antibacterial agent with IC50 values of 0.783 μM and 7.136 μM against E. coli DNA gyrase and topoisomerase IV, respectively. DNA gyrase/Topo IV-IN-2 exhibits broad-spectrum antibacterial efficacy against both Gram-positive and Gram-negative pathogens. DNA gyrase/Topo IV-IN-2 can inhibit the biofilms of B. subtilis and MRSA, with an MIC of 1.9 μM against both B. subtilis and MRSA. DNA gyrase/Topo IV-IN-2 can be used in research related to anti-drug-resistant bacterial drugs[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial; DNA/RNA Synthesis; Topoisomerase
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O=CC1=CC=C(OC)C(OCC2=CN(CCCCCOC3=CC(O4)=C(C=C3)C=CC4=O)N=N2)=C1
Molecular Formula
C25H25N3O6
Molecular Weight
463.48
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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