SRI-32743

SRI-32743 is an allosteric human dopamine transporter (hDAT) modulator (IC50=9.86 μM) . SRI-32743 is promising for research of HIV-Tat-induced neurotoxicity[1].

Product Specifications

CAS Number

[1940118-42-2]

UNSPSC

12352005

Target

Dopamine Transporter; HIV; HIV Protease

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Neuronal Signaling

Field of Research

Infection; Neurological Disease

Smiles

CCC(CNC1=NC(C(C(C)=C2)=CN3C2=NC=C3)=NC4=CC=CC=C14)C5=CC=CC=C5

Molecular Formula

C26H25N5

Molecular Weight

407.51

References & Citations

[1]N- (2-phenylbutyl) -5,6,7,8-tetrahydro-quinazolin-4-amines as allosteric modulators of HIV-DAT-tat interaction. Bioorg Med Chem Lett. 2025 Dec 1;128:130345.