SRI-32743
SRI-32743 is an allosteric human dopamine transporter (hDAT) modulator (IC50=9.86 μM) . SRI-32743 is promising for research of HIV-Tat-induced neurotoxicity[1].
Product Specifications
CAS Number
1940118-42-2
UNSPSC
12352005
Target
Dopamine Transporter; HIV; HIV Protease
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Neuronal Signaling
Field of Research
Infection; Neurological Disease
Smiles
CCC(CNC1=NC(C(C(C)=C2)=CN3C2=NC=C3)=NC4=CC=CC=C14)C5=CC=CC=C5
Molecular Formula
C26H25N5
Molecular Weight
407.51
References & Citations
[1]N- (2-phenylbutyl) -5,6,7,8-tetrahydro-quinazolin-4-amines as allosteric modulators of HIV-DAT-tat interaction. Bioorg Med Chem Lett. 2025 Dec 1;128:130345.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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