Sn-Glycero-3-phosphocholine (Standard)

Sn-Glycero-3-phosphocholine (Standard) is the analytical standard of sn-Glycero-3-phosphocholine. This product is intended for research and analytical applications. sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia[1][2].

Product Specifications

CAS Number

[28319-77-9]

Product Name Alternative

Choline Alfoscerate (Standard) ; Alpha-GPC (Standard) ; L-α-GPC (Standard)

UNSPSC

12352211

Target

Cholinesterase (ChE) ; Endogenous Metabolite; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling; Others

Field of Research

Neurological Disease

Purity

99.71

Smiles

O=P(OCC[N+](C)(C)C)(OC[C@H](O)CO)[O-]

Molecular Formula

C8H20NO6P

Molecular Weight

257.22

References & Citations

[1]Lee SH, et al. Late treatment with choline alfoscerate (l-alpha glycerylphosphorylcholine, α-GPC) increases hippocampal neurogenesis and provides protection against seizure-induced neuronal death and cognitive impairment. Brain Res. 2017 Jan 1;1654 (Pt A) :66-76.|[2]Traini E, et al. Choline alphoscerate (alpha-glyceryl-phosphoryl-choline) an old choline- containing phospholipidwith a still interesting profile as cognition enhancing agent. Curr Alzheimer Res. 2013 Dec;10 (10) :1070-9.