ALK ligand-Linker Conjugate 1
ALK ligand-Linker Conjugate 1 is a ALK ligand-linker conjugate that can be used for synthesis of PROTAC ALK degrader-4 (HY-175527) [1].
Product Specifications
CAS Number
[2796974-34-8]
UNSPSC
12352005
Target
Anaplastic lymphoma kinase (ALK) ; Target Protein Ligand-Linker Conjugates
Related Pathways
PROTAC; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(CN1CCN(CC1)C2CCN(CC2)C3=C(C=C4C(C(C)(C5=C(C4=O)C(C=CC(C#N)=C6)=C6N5)C)=C3)CC)OC(C)(C)C
Molecular Formula
C36H45N5O3
Molecular Weight
595.77
References & Citations
[1]Xie S, et al. Overcoming E3 Ligase-Mediated Resistance: Development of Novel Hydrophobic Tagging-Based Degraders Targeting ALK Protein. J Med Chem. 2025 Aug 14;68 (15) :15579-15597.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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