MAO-B-IN-48
MAO-B-IN-48 is a selective MAO-B inhibitor (IC50 = 0.09 μM, Ki = 0.02 μM) . MAO-B-IN-48 exhibits inhibitory activity against hBChE (IC50 = 1.10 μM, Ki = 0.43 μM) and AChE (IC50 = 0.56 μM, Ki = 0.14 μM) . MAO-B-IN-48 suppresses self-induced aggregation of toxic β-amyloid peptides and exerts antioxidant activity, including DPPH radical scavenging, CUPRAC copper ion reduction, and superoxide anion scavenging. MAO-B-IN-48 can be used for the study of Alzheimer's disease (AD) [1].
Product Specifications
UNSPSC
12352100
Target
Amyloid-β; Cholinesterase (ChE) ; Monoamine Oxidase
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
C[C@H](C1=CC=CC2=C1C=CC=C2)NC(OC3=CC(N(C)C)=CC=C3)=S
Molecular Formula
C21H22N2OS
Molecular Weight
350.48
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE; MAO-A; MAO-B
Frequently Asked Questions
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