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5-HT2A agonist 7

5-HT2A agonist 7 (Compound 45) is an orally active and highly selective serotonin receptor 2A (5-HT2A) agonist (EC50=12 nM) . 5-HT2A agonist 7 is promising for research of psychiatric disorders such as depression[1].

Product Specifications

CAS Number

2864368-10-3

UNSPSC

12352005

Target

5-HT Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

COC1=C(C=C(C(C(F)(F)F)=C1)SC)C2CCCNC2

Molecular Formula

C14H18F3NOS

Molecular Weight

305.36

References & Citations

[1]Sabnis RW. Novel Compounds as 5‑HT2A Agonists for Treating Depression. ACS Med Chem Lett. 2025 Jul 31;16 (8) :1522-1523.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT2 Receptor

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