5-HT2A agonist 6

5-HT2A agonist 6 (compound 2-6) is a 5-HT2A agonist with an EC50 of 1.7 nM. 5-HT2A agonist 6 is used in the study of stress-related disorders, namely depression, anxiety, and post-traumatic stress disorder[1].

Product Specifications

CAS Number

3044091-48-4

UNSPSC

12352100

Target

5-HT Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

COC1=CC(CCNCC2=C(C=CC=C2)OC)=C(C=C1S(C)(=N)=O)OC

Molecular Formula

C19H26N2O4S

Molecular Weight

378.49

References & Citations

[1]Sabnis RW. Novel Non-hallucinogenic Neurite Growth Compounds as 5‑HT2A Agonists for Treating Stress-Related Disorders, Namely Depression, Anxiety, and PTSD. ACS Med Chem Lett. 2025 Jul 30;16 (8) :1524-1525