LysRs-IN-4

LysRS-IN-4 (Compound 49) is an orally active Mycobacterium tuberculosis LysRS (lysyl-tRNA synthetase) inhibitor. LysRS-IN-4 is promising for research of tuberculosis[1].

Product Specifications

CAS Number

[2973324-63-7]

UNSPSC

12352005

Target

Bacterial; STING

Related Pathways

Anti-infection; Immunology/Inflammation

Field of Research

Infection

Smiles

COC1=C(C(N([C@H]2[C@H](CCCCC2(F)F)O)C3)=O)C3=NC(N)=N1

Molecular Formula

C14H18F2N4O3

Molecular Weight

328.31

References & Citations

[1]Davis SH, et al. Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis. J Med Chem. 2025 Aug 14;68 (15) :16459-16482.