D-CS319
D-CS319 is a potent inhibitor of metallo-𝛽-lactamases (MBLs) with IC50 values of 2.0 and 3.0 μM for IMP-1 and IMP-78, respectively. D-CS319 has antibacterial activity[1].
Product Specifications
CAS Number
1770826-25-9
UNSPSC
12352100
Target
Bacterial; Beta-lactamase
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
[H][C@@]12CS[C@H](N1[C@H](CS2)C(O)=O)CS
Molecular Formula
C7H11NO2S3
Molecular Weight
237.36
References & Citations
[1]Thomas CA, et al. Inhibitor Affinity Differs among Clinical Variants of IMP Metallo-β-Lactamases: Analysis and Implications for Inhibitor Design. ACS Infect Dis. 2025 Aug 8;11 (8) :2157-2168.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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