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CB2R agonist 4

CB2R agonist 4 is a cannabinoid receptor 2 (CB2R) agonist with an EC50 value of 6.9 μM. CB2R agonist 4 can induce cell apoptosis, ROS production and protein misfolding. CB2R agonist 4 shows cytotoxicity to a panel of tumor cell lines. CB2R agonist 4 can be used for the research of cancer[1].

Product Specifications

CAS Number

[182496-82-8]

UNSPSC

12352005

Target

Apoptosis; Cannabinoid Receptor; Reactive Oxygen Species (ROS)

Related Pathways

Apoptosis; GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(OCC1=CC=CC=C1)[C@@H](N2C(C3=CC=CC=C3NC2=O)=O)CC(C)C

Molecular Formula

C21H22N2O4

Molecular Weight

366.41

References & Citations

[1]Ciaglia T, et al. Untargeted Diversity-Oriented Synthesis for the Discovery of New Antitumor Agents: An Integrated Approach of Inverse Virtual Screening, Bioinformatics, and Omics for Target Deconvolution. J Med Chem. 2025 Aug 14;68 (15) :16483-16517.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-175481/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CB2

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