RXR agonist 2
RXR agonist 2 (Compound 22) is a highly selective retinoid X receptor (RXR) agonist (EC50=0.039 μM) . RXR agonist 2 is promising for research of metabolic syndrome and Alzheimer's disease[1].
Product Specifications
UNSPSC
12352005
Target
RAR/RXR
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease; Neurological Disease
Smiles
OC(C1=CC=C2C(N[C@H]([C@@]3([H])[C@]2([H])[C@@H]4CC[C@H]3C4)C5=CC(C(F)(F)F)=CC(C(F)(F)F)=C5)=C1C)=O
Molecular Formula
C24H21F6NO2
Molecular Weight
469.42
References & Citations
[1]Nawa F, et al. Development of an RXR Agonist Scaffold with Pronounced Homodimer Preference. J Med Chem. 2025 Aug 14;68 (15) :16172-16187.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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