Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

SMI-10B13

SMI-10B13 is an Oncostatin M (OSM) inhibitor with a KD of 6.6 μM. SMI-10B13 inhibits OSM-mediated STAT3 phosphorylation in T47D and MCF-7 cell lines (IC50 = 136 and 164 nM, respectively) . SMI-10B13 shows anti-tumor effect in human breast cancer mice models[1].

Product Specifications

CAS Number

2502294-68-8

UNSPSC

12352005

Target

Interleukin Related; STAT

Related Pathways

Immunology/Inflammation; JAK/STAT Signaling; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

O=C(/C=C/C1=CC(C2=CC3=C(C=C2)C=CN3)=C(O1)C4=CC=C5C=CNC5=C4)O

Molecular Formula

C23H16N2O3

Molecular Weight

368.38

References & Citations

[1]Wolf CL, et al. Development of the First Small-Molecule Inhibitor Targeting Oncostatin M for Treatment of Breast Cancer. J Med Chem. 2025 Aug 14;68 (15) :15422-15445.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

RASL12 (FITC)
574310-01 50 µg

RASL12 (FITC)

Sign In for Pricing
View Details
RASL12 (FITC)
574310-02 100 µg

RASL12 (FITC)

Sign In for Pricing
View Details
CAMTA1 discontinued
308982 100 µL

CAMTA1 discontinued

Sign In for Pricing
View Details
PSAP (Cerebroside Sulfate Activator, FLJ00245, GLBA, MGC110993, Prosaposin, SAP1) (MaxLight 405) discontinued
131919-ML405 100 µL

PSAP (Cerebroside Sulfate Activator, FLJ00245, GLBA, MGC110993, Prosaposin, SAP1) (MaxLight 405) discontinued

Sign In for Pricing
View Details
S119-8 5mg
A20225-5 5 mg

S119-8 5mg

Sign In for Pricing
View Details
Oxamflatin
MBS5755318 Inquire

Oxamflatin

Sign In for Pricing
View Details