AVI-4206
AVI-4206 is a selective Mac1 inhibitor with an lC50 of 64 nM. AVI-4206 reduces viral replication, restores an interferon response, and leads to a survival benefit in an animal model of SARS-CoV-2 infection. AVI-4206 can be used the study of SARS-CoV-2 infection[1].
Product Specifications
CAS Number
[3105041-48-0]
UNSPSC
12352005
Target
SARS-CoV
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O=C(NCC)NC1=CC=CC2=C1NC3=NC=NC(NN4C(C)(C)CCC4=O)=C32
Molecular Formula
C19H23N7O2
Molecular Weight
381.43
References & Citations
[1]Suryawanshi RK, et al. The Mac1 ADP-ribosylhydrolase is a Therapeutic Target for SARS-CoV-2. bioRxiv [Preprint]. 2024 Aug 29:2024.08.08.606661.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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