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SARS-CoV-2-IN-117

SARS-CoV-2-IN-117 (Compound C19) is a SARS-CoV-2 E protein inhibitor. SARS-CoV-2-IN-117 significantly inhibits SARS-CoV-2 E protein interaction with host ZO-1 PDZ2 domain. SARS-CoV-2-IN-117 has potent antiviral activity and significantly reduces viral replication. SARS-CoV-2-IN-117 can be used for COVID-19 research[1].

Product Specifications

CAS Number

[866036-65-9]

UNSPSC

12352005

Target

SARS-CoV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(C1=CC=C2C=CC(/C=C/C3=CC=C(OC)C(OC)=C3)=NC2=C1OC)C4=CC=CC=C4[N+]([O-])=O

Molecular Formula

C27H22N2O6

Molecular Weight

470.47

References & Citations

[1]Alvarez F, et al. HTRF-based identification of small molecules targeting SARS-CoV-2 E protein interaction with ZO-1 PDZ2[J]. bioRxiv, 2025: 2025.07. 16.665136.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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