AR-DBD ligand-1
AR-DBD ligand-1 is an AR-DBD ligand. AR-DBD ligand-1 can be used to synthesize PROTAC LYA914 (HY-175455) [1].
Product Specifications
UNSPSC
12352005
Target
Androgen Receptor; Ligands for Target Protein for PROTAC
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
COC1=C(F)C(F)=CC=C1C2=CSC(N3CCNCC3)=N2
Molecular Formula
C14H15F2N3OS
Molecular Weight
311.35
References & Citations
[1]Lv Y, et al. Discovery of LYA914, An Orally Bioavailable PROTAC Degrader Targeting the DNA Binding Domain of the Androgen Receptor for the Treatment of CRPC. J Med Chem. 2025 Jul 28.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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