MRT-10350
MRT-10350 (Compound 2) is a cereblon-based HCK molecular glue degrader. MRT-10350 can be used for cancers like chronic myeloid leukemia and HIV-1 infections research[1].
Product Specifications
UNSPSC
12352005
Target
Molecular Glues; Src
Related Pathways
PROTAC; Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Smiles
O=C(NC1(C2=CC=C(SC)C=C2)COCC1)NC3=CC4=C(C(N(C(CC5)C(NC5=O)=O)C4)=O)C=C3
Molecular Formula
C25H26N4O5S
Molecular Weight
494.56
References & Citations
[1]Petzold G, et al. Mining the CRBN target space redefines rules for molecular glue-induced neosubstrate recognition. Science. 2025 Jul 3;389 (6755) :eadt6736.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Hck
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