GDC-0152-amide-PEG2-acid
Pomalidomide-C9-Br is a synthesized E3 ligase ligand-linker conjugate that can be used to synthesize GNE-5472 (HY-175445) [1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
CN[C@@H](C)C(N[C@@H](C1CCCCC1)C(N2CCC[C@H]2C(NC(S3)=C(C4=CC=CC=C4)N=C3NC(CCOCCOCCC(O)=O)=O)=O)=O)=O
Molecular Formula
C34H48N6O8S
Molecular Weight
700.85
References & Citations
[1]Shemorry A, et al. Engineering ERα degraders with pleiotropic ubiquitin ligase ligands maximizes therapeutic efficacy by co-opting distinct effector ligases. Cell Chem Biol. 2025 May 15;32 (5) :694-709.e35.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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