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GDC-0152-amide-PEG2-acid

Pomalidomide-C9-Br is a synthesized E3 ligase ligand-linker conjugate that can be used to synthesize GNE-5472.

Product Specifications

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

CN[C@@H](C)C(N[C@@H](C1CCCCC1)C(N2CCC[C@H]2C(NC(S3)=C(C4=CC=CC=C4)N=C3NC(CCOCCOCCC(O)=O)=O)=O)=O)=O

Molecular Formula

C34H48N6O8S

Molecular Weight

700.85

References & Citations

[1]Shemorry A, et al. Engineering ERα degraders with pleiotropic ubiquitin ligase ligands maximizes therapeutic efficacy by co-opting distinct effector ligases. Cell Chem Biol. 2025 May 15;32 (5) :694-709.e35.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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