AMPA receptor modulator-8
AMPA receptor modulator-8 (Example 270) is a AMPA receptor modulator with an IC50 of 0.02 nM for TARP-γ2. AMPA receptor modulator-8 can be used for nervous diseases like epilepsy, Alzheimer's disease and Parkinson's disease research[1].
Product Specifications
CAS Number
[2034182-75-5]
UNSPSC
12352005
Target
IGluR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC(F)(C1=NC2=C(C=C1)N=C(C(F)(F)F)N2C3=CC4=C(NN=C4)C(Cl)=C3)F
Molecular Formula
C15H6ClF6N5
Molecular Weight
405.69
References & Citations
[1]BERRY C G.B, et al. Azabenzimidazoles and their use as ampa receptor modulators. WO2016176460A1. 2016-11-03.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Recombinant Shewanella loihica UPF0758 protein Shew_3481 (Shew_3481)
Recombinant Shewanella loihica UPF0758 protein Shew_3481 (Shew_3481)