Carbonic anhydrase activator 1
Carbonic anhydrase activator 1 (Compound 17) is an orally active and a BBB-penetrable Carbonic anhydrase (CA) activator with KAs of 7.8, 3.9 and 2.1 μM for hCA I, hCA VA and hCA VII. Carbonic anhydrase activator 1 can be used for cancers, glaucoma, cardiovascular diseases and neurodegenerative disorders like epilepsy research[1].
Product Specifications
CAS Number
[2374923-30-3]
UNSPSC
12352005
Target
Carbonic Anhydrase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Neurological Disease; Cardiovascular Disease
Smiles
N#CC1=C(C2=CC=CO2)C(C#N)=C(N)N=C1SCC3=CC=NC=C3
Molecular Formula
C17H11N5OS
Molecular Weight
333.37
References & Citations
[1]Vigiani E, et al. Repurposing the amino-3,5-dicyanopyridine scaffold from adenosine receptor ligands to carbonic anhydrase activators. Eur J Med Chem. 2025 Jul 5;291:117578.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-175441/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA
Curated Selection
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