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P38 MAPK-IN-8

P38 MAPK-IN-8 (Compound 8) is an orally active, potent and selective p38 mitogen-activated protein kinase (p38 MAPK) inhibitor. p38 MAPK-IN-8 is promising for research of inflammatory responses, autoimmune diseases, and cancer[1].

Product Specifications

CAS Number

208182-49-4

UNSPSC

12352005

Target

P38 MAPK

Related Pathways

MAPK/ERK Pathway

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Smiles

FC1=CC=C(C2=C(C3=CC=NC=C3)N=C(C4=CC=C(C)C=C4)N2)C=C1

Molecular Formula

C21H16FN3

Molecular Weight

329.37

References & Citations

[1]Chang LL, et al. Substituted imidazoles as glucagon receptor antagonists. Bioorg Med Chem Lett. 2001 Sep 17;11 (18) :2549-53.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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