P38 MAPK-IN-8
P38 MAPK-IN-8 (Compound 8) is an orally active, potent and selective p38 mitogen-activated protein kinase (p38 MAPK) inhibitor. p38 MAPK-IN-8 is promising for research of inflammatory responses, autoimmune diseases, and cancer[1].
Product Specifications
CAS Number
[208182-49-4]
UNSPSC
12352005
Target
P38 MAPK
Related Pathways
MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Smiles
FC1=CC=C(C2=C(C3=CC=NC=C3)N=C(C4=CC=C(C)C=C4)N2)C=C1
Molecular Formula
C21H16FN3
Molecular Weight
329.37
References & Citations
[1]Chang LL, et al. Substituted imidazoles as glucagon receptor antagonists. Bioorg Med Chem Lett. 2001 Sep 17;11 (18) :2549-53.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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