TNF-α-IN-26
TNF-α-IN-26 (Compound 18) is a TNF-α inhibitor with an IC50 of 0.10 μM for CSBP ligands. TNF-α-IN-26 inhibits LPS (HY-D1056) -stimulated TNF production in mice model. TNF-α-IN-26 can be used for inflammatory diseases research[1].
Product Specifications
CAS Number
[165806-63-3]
UNSPSC
12352005
Target
TNF Receptor
Related Pathways
Apoptosis
Field of Research
Inflammation/Immunology
Smiles
FC1=CC=C(C2=C(C3=CC=NC=C3)N(CCCOCC)C=N2)C=C1
Molecular Formula
C19H20FN3O
Molecular Weight
325.38
References & Citations
[1]Boehm JC, et al. 1-substituted 4-aryl-5-pyridinylimidazoles: a new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potency. J Med Chem. 1996 Sep 27;39 (20) :3929-37.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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