DHODH-IN-30
DHODH-IN-30 (compound 4g) is a potent human dihydroorotate dehydrogenase (hDHODH) inhibitor with an IC50 of 32 nM. DHODH-IN-30 exhibits protective effects against oxidative stress[1].
Product Specifications
UNSPSC
12352005
Target
Dihydroorotate Dehydrogenase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
O=C(O)[C@H](CC1=CC=C(O)C=C1)N(C2=O)C(C3=C2C4=CC=CC=C4N=C3C)=O
Molecular Formula
C21H16N2O5
Molecular Weight
376.36
References & Citations
[1]Dimitrijević MG, et al. First bioconjugates in the role of highly effective human dihydroorotate dehydrogenase inhibitors: Synthesis, pharmacological, toxicological and hydrolytic stability studies of α-amino acid-modified pyrrolo[3,4-c]quinoline-1,3-dione scaffold. Eur J Med Chem. 2025 Nov 5;297:117972.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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