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VH032-cyclopropane-F-C4-CHO

VH032-cyclopropane-F-C4-CHO is an E3 ubiquitinase ligand-linker conjugate. VH032-cyclopropane-F-C4-CHO can be used to synthesize LC-MF-4 (HY-174981) [1].

Product Specifications

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=CCCCCOC1=CC(C2=C(N=CS2)C)=CC=C1CNC([C@@H]3C[C@H](CN3C([C@H](C(C)(C)C)NC(C4(CC4)F)=O)=O)O)=O

Molecular Formula

C31H41FN4O6S

Molecular Weight

616.74

References & Citations

[1]Zheng L, et al. LC-MF-4, a Novel FGFR3 Degrader for Therapeutic Intervention in FGFR3-Altered Cancers. J Med Chem. 2025 Jul 10;68 (13) :13858-13871.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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