ICP-103
ICP-103 (Compound 3K) is a highly selective protein kinase C (PKC) inhibitor with an IC50 of 30 nM. ICP-103 is promising for research of cancers[1][2].
Product Specifications
CAS Number
153997-72-9
UNSPSC
12352005
Target
PKC
Related Pathways
Epigenetics; TGF-beta/Smad
Field of Research
Cancer
Smiles
N#CCCN(C1=C2C(C(NC3=O)=O)=C3C4=C1N(C)C5=C4C=CC=C5)C6=C2C=CC=C6
Molecular Formula
C24H16N4O2
Molecular Weight
392.41
References & Citations
[1]Kleinschroth J, Hartenstein J, Rudolph C, et al. Novel indolocarbazole protein kinase C inhibitors with improved biochemical and physicochemical properties[J]. Bioorganic & Medicinal Chemistry Letters, 1995, 5 (1) : 55-60.|[2]Roy S, Eastman A, Gribble G W. Synthesis of 7‐keto‐Gö6976 (ICP‐103) [J]. Synthetic communications, 2005, 35 (4) : 595-601.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
