OZO-Cl
OZO-Cl is an OZO derivative. OZO-Cl has anti-cancer activity. OZO-Cl significantly decreases the intracellular glutathion S-transferase Pi (GST) activity. OZO-Cl exhibits cytotoxicity to cancer cell lines, with IC50s of 150 and 120 μmol/L in Panc-1 and K562 cells respectively[1].
Product Specifications
CAS Number
2201798-21-0
UNSPSC
12352101
Target
Glutathione S-transferase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
[O-]C1=C(C2=CC=C(Cl)C=C2)[S+]=NO1
Molecular Formula
C8H4ClNO2S
Molecular Weight
213.64
References & Citations
[1]Cui, H., et al., (2008) . 4-Aryl-1,3,2-oxathiazolylium-5-olate: a novel GST inhibitor to release JNK and activate c-Jun for cancer therapy. Cancer chemotherapy and pharmacology, 62 (3), 509–515.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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