D-myo-Inositol-4,5-diphosphate (sodium)
D-myo-Inositol-4,5-diphosphate (sodium) is one of the members in inositol phosphate family of second messengers that play an important role in transmitting cellular signals. D-myo-Inositol-4,5-diphosphate (sodium) can open calcium channels and increase intracellular calcium upon binding to its receptor on the endoplasmic reticulum[1][2][3].
Product Specifications
CAS Number
208584-57-0
Product Name Alternative
Ins (4,5) -P2 (sodium) ; 4,5-IP2 (sodium)
UNSPSC
12352211
Target
Endogenous Metabolite
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Smiles
O[C@@H]1[C@H]([C@@H]([C@H]([C@H]([C@H]1O)O)O)OP(O)(O[Na])=O)OP(O)(O[Na])=O
Molecular Formula
C6H12Na2O12P2
Molecular Weight
384.08
References & Citations
[1]Streb, H., et al., (1983) . Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate. Nature, 306 (5938), 67–69. |[2]Mikoshiba, K., et al., (1993) . Structure and function of inositol 1,4,5-trisphosphate receptor. Annals of the New York Academy of Sciences, 707, 178–197. |[3]Exton J. H. (1996) . Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annual review of pharmacology and toxicology, 36, 481–509. |[4]Yang, X., et al., (1999) . Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate. The Journal of biological chemistry, 274 (27), 18973–18980.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC680460-100 1x 100 µL
CD44 Standard (156-3C11), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC402216-100 1x 100 µL
CD50 / ICAM3 (CG106), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
