D-myo-Inositol-1,2,6-triphosphate (sodium)

D-myo-Inositol-1,2,6-triphosphate (sodium) is one of the members in inositol phosphate family of second messengers that play an important role in transmitting cellular signals. D-myo-Inositol-1,2,6-triphosphate (sodium) can open calcium channels and increase intracellular calcium upon binding to its receptor on the endoplasmic reticulum[1][2][3][4].

Product Specifications

Product Name Alternative

Ins (1,2,6) -P3; 1,2,6-IP3

UNSPSC

12352211

Target

Calcium Channel

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Others

Smiles

O[C@H]1[C@H]([C@H]([C@@H]([C@H]([C@@H]1O)O)OP(O)(O[Na])=O)OP(O)(O[Na])=O)OP(O)(O[Na])=O

Molecular Formula

C6H12Na3O15P3

Molecular Weight

486.04

References & Citations

[1]Majerus P. W. (1992) . Inositol phosphate biochemistry. Annual review of biochemistry, 61, 225–250. |[2]Berridge M. J. (2009) . Inositol trisphosphate and calcium signalling mechanisms. Biochimica et biophysica acta, 1793 (6), 933–940. |[3]Yoshida, Y., & Imai, S. (1997) . Structure and function of inositol 1,4,5-trisphosphate receptor. Japanese journal of pharmacology, 74 (2), 125–137.|[4]Exton J. H. (1996) . Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annual review of pharmacology and toxicology, 36, 481–509.