RIPK1-ligand-2
RIPK1-ligand-2 is a RIPK1 inhibitor. RIPK1-ligand-2 can be used for synthesis of PROTAC RIPK1 Degrader-1 (HY-175370) [1].
Product Specifications
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; RIP kinase
Related Pathways
Apoptosis; PROTAC
Field of Research
Cancer
Smiles
O=C(O)CN1C=C(C=N1)C2=CN=C(N)C3=C2SC=C3C4=CC=C5N(C(CC6=CC=CC=C6)=O)CCC5=C4
Molecular Formula
C28H23N5O3S
Molecular Weight
509.58
References & Citations
[1]Zhang Z, et al. Development of Potent and Selective RIPK1 Degraders Targeting Its Nonenzymatic Function for Cancer Treatment. J Med Chem. 2025 Jul 24;68 (14) :15120-15136.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
RIPK1
Curated Selection
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