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RIPK1-ligand-2

RIPK1-ligand-2 is a RIPK1 inhibitor. RIPK1-ligand-2 can be used for synthesis of PROTAC RIPK1 Degrader-1.

Product Specifications

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC; RIP kinase

Related Pathways

Apoptosis; PROTAC

Field of Research

Cancer

Smiles

O=C(O)CN1C=C(C=N1)C2=CN=C(N)C3=C2SC=C3C4=CC=C5N(C(CC6=CC=CC=C6)=O)CCC5=C4

Molecular Formula

C28H23N5O3S

Molecular Weight

509.58

References & Citations

[1]Zhang Z, et al. Development of Potent and Selective RIPK1 Degraders Targeting Its Nonenzymatic Function for Cancer Treatment. J Med Chem. 2025 Jul 24;68 (14) :15120-15136.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

RIPK1

Frequently Asked Questions

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