(E) -Selinexor
(E) -Selinexor ((E) -KPT-330) is the E-isomer of Selinexor. Selinexor is the selective, orally active CRM1 inhibitor[1].
Product Specifications
CAS Number
1421923-86-5
Product Name Alternative
(E) -KPT-330
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
CRM1
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(NNC1=NC=CN=C1)/C=C/N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2
Molecular Formula
C17H11F6N7O
Molecular Weight
443.31
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Rashal T, et al., Methods of promoting wound healing using crm1 inhibitors. WO2014144772.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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