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(E) -Selinexor

(E) -Selinexor ((E) -KPT-330) is the E-isomer of Selinexor (HY-17536) . Selinexor is the selective, orally active CRM1 inhibitor[1].

Product Specifications

CAS Number

[1421923-86-5]

Product Name Alternative

(E) -KPT-330

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

CRM1

Related Pathways

Membrane Transporter/Ion Channel

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(NNC1=NC=CN=C1)/C=C/N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2

Molecular Formula

C17H11F6N7O

Molecular Weight

443.31

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Rashal T, et al., Methods of promoting wound healing using crm1 inhibitors. WO2014144772.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Curated Selection

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