DENV-IN-13

DENV-IN-13 (Compound 30) is a DENV2 protease inhibitor with an EC50 of 9.8 μM for DENV2 protease in HeLa cells. DENV-IN-13 has potent antiviral activity with negligible cytotoxicity and no inhibition of the off-targets thrombin and trypsin. DENV-IN-13 can be used for flaviviral infections research[1].

Product Specifications

UNSPSC

12352005

Target

Dengue Virus

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(C1=NN(C(C2=CC=CC=C2)=C1)C3=CC=CC=C3)NC4=CC(CO)=CC=C4

Molecular Formula

C23H19N3O2

Molecular Weight

369.42

References & Citations

[1]Lang J, et al. Discovery of Pyrazole-3-Carboxylic Acid Derivatives as Dengue Virus Protease Inhibitors with Antiviral Activity[J]. ACS Medicinal Chemistry Letters, 2025.