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Tyrosinase-IN-43

Tyrosinase-IN-43 (Compound 12j) is a competitive Tyrosinase inhibitor with an IC50 of 10.49 μM for tyrosinase. Tyrosinase-IN-43 has significant antioxidant activity. Tyrosinase-IN-43 can be used for hyperpigmentation-related complications such as melasma, freckles, age spots and post-inflammatory hyperpigmentation research[1].

Product Specifications

UNSPSC

12352005

Target

Tyrosinase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

O=C(NCCC1=CC=CC=C1)CSC2=NC3=CC=CC=C3C=C2/C=N/N4C(S)=NN=C4C5=CC=CC=C5

Molecular Formula

C28H24N6OS2

Molecular Weight

524.66

References & Citations

[1]Motamedi Shakib N, et al. Development of mercapto-phenyl-1,2,4-triazole bearing thio-quinoline as a novel class of tyrosinase inhibitors: an in vitro and in silico study. Sci Rep. 2025 Jul 14;15 (1) :25382.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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