HPK1-IN-60
HPK1-IN-60 (Compound 1) is a HPK1 inhibitor. HPK1-IN-60 can be used for antitumor immunotherapy research[1].
Product Specifications
CAS Number
[2421199-24-6]
UNSPSC
12352005
Target
MAP4K
Related Pathways
MAPK/ERK Pathway
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C1N(C2=NC(C3=NN=CN3CCC)=CC=C2)CC4=C1C=C(N(C)C)N=C4CNC
Molecular Formula
C21H26N8O
Molecular Weight
406.48
References & Citations
[1]Zhou D, et al. Development of a Scalable Synthesis of a HPK1 Inhibitor Featuring a Direct α-Arylation of Boc-Protected N, N-Dimethylamine by Palladium-Mediated Negishi Cross-Coupling. J Org Chem. 2025 Aug 1;90 (30) :10690-10701.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAP4K1/HPK1
Curated Selection
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