C-Met ligand-Linker Conjugate 2
C-Met ligand-Linker Conjugate 2 is a synthesized target protein ligand-linker conjugate that can be used for synthesis of PROTACs, such as PROTAC c-Met degrader-6 (HY-175321) . PROTAC c-Met degrader-6 is a c-Met PROTAC degrader with anti-tumor activity[1].
Product Specifications
CAS Number
[1103505-24-3]
UNSPSC
12352005
Target
C-Met/HGFR; Target Protein Ligand-Linker Conjugates
Related Pathways
PROTAC; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
N#CC1=CC=CC(C2=NN(C(C=C2)=O)CC3=CC(C(N=C4)=NC=C4OCCN5CCNCC5)=CC=C3)=C1
Molecular Formula
C28H27N7O2
Molecular Weight
493.56
References & Citations
[1]Jia C, et al. Novel Highly Potent c-Met Degraders against a Broad Range of Cancers. J Med Chem. 2025 Jul 24;68 (14) :15176-15197.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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