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C-Met ligand-Linker Conjugate 2

C-Met ligand-Linker Conjugate 2 is a synthesized target protein ligand-linker conjugate that can be used for synthesis of PROTACs, such as PROTAC c-Met degrader-6. PROTAC c-Met degrader-6 is a c-Met PROTAC degrader with anti-tumor activity[1].

Product Specifications

CAS Number

1103505-24-3

UNSPSC

12352005

Target

C-Met/HGFR; Target Protein Ligand-Linker Conjugates

Related Pathways

PROTAC; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

N#CC1=CC=CC(C2=NN(C(C=C2)=O)CC3=CC(C(N=C4)=NC=C4OCCN5CCNCC5)=CC=C3)=C1

Molecular Formula

C28H27N7O2

Molecular Weight

493.56

References & Citations

[1]Jia C, et al. Novel Highly Potent c-Met Degraders against a Broad Range of Cancers. J Med Chem. 2025 Jul 24;68 (14) :15176-15197.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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