ALR2-IN-7
ALR2-IN-7 (Compound 5a) is a highly potent and selective aldose reductase (ALR2/AKR1B1) inhibitor (Ki=8.71 nM) . ALR2-IN-7 is promising for research of diabetic complications (e.g., retinopathy, nephropathy) and cancers[1].
Product Specifications
CAS Number
[59935-47-6]
UNSPSC
12352005
Target
Aldose Reductase
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease
Concentration
10mM
Purity
99.94
Solubility
DMSO : 17.5 mg/mL (ultrasonic)
Smiles
O=C(O)CCC(NC1=CC(CC2=C3C=CC=C2)=C3C=C1)=O
Molecular Formula
C17H15NO3
Molecular Weight
281.31
References & Citations
[1]Gundogdu S, et al. Fluorenyl-phthalimide hybrids as potent aldose reductase inhibitors with selective anticancer activity: Rational design, synthesis, and molecular insights. Bioorg Chem. 2025 Aug;163:108689.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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