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FAP-IN-6

FAP-IN-6 (Compound 21) is a selectivity FAP inhibitor with an IC50 of 13 pM. FAP-IN-6 has a high metabolic stability. FAP-IN-6 labeled with 18F can be used as a positron emission tomography (PET) tracer. FAP-IN-6 can be used for microenvironment of cancers research[1].

Product Specifications

UNSPSC

12352005

Target

FAP

Related Pathways

Immunology/Inflammation

Field of Research

Cancer

Smiles

O=C(C1=CC=NC2=CC=C(C=C21)N(CCCN3N=NC(COCCOCCOCCF)=C3)C)NCC(N4CCC[C@H]4C#N)=O

Molecular Formula

C30H39FN8O5

Molecular Weight

610.68

References & Citations

[1]Köchel R, et al. Novel [18F]Fluorine-Based PET Tracers with Polar But Nonbasic Linkers to Image the Fibroblast Activation Protein in the Microenvironment of Tumors. J Med Chem. 2025 Jul 17.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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