LIBX-A402
LIBX-A402 (Compound 15b) is a selective ACSL4inhibitor with an IC50 of 0.33 μM. LIBX-A402 significantly protects MDA-MB-231 and LUHMES cells from ferroptosis. LIBX-A402 can be used for cancer, ischemia-reperfusion injury and neurodegenerative diseases like Parkinson’s disease research[1].
Product Specifications
UNSPSC
12352005
Target
Ferroptosis
Related Pathways
Apoptosis
Field of Research
Cancer; Neurological Disease; Cardiovascular Disease
Smiles
O=C(C1=C(C2=CC(C)=CC=C2O1)NC(C)=O)C3=CC=CC=C3
Molecular Formula
C18H15NO3
Molecular Weight
293.32
References & Citations
[1]Mazhari Dorooee D, et al. LIBX-A401: A Novel Selective Inhibitor of Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) and Its Binding Mode. Angew Chem Int Ed Engl. 2025 May;64 (19) :e202500518.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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