MG-HuR2
MG-HuR2 is a molecular glue degrader targeting the oncogenic RNA-binding protein HuR (IC50=0.5 μM) . MG-HuR2 is promising for research of HuR-overexpressing malignancies (e.g., breast cancer) [1].
Product Specifications
UNSPSC
12352005
Target
HuR; Molecular Glues
Related Pathways
Epigenetics; PROTAC
Field of Research
Cancer
Concentration
10mM
Purity
98.70
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCOC(C1=CC2=CC(NC(/C=C/C(C3=CC=C(C=C3)OC)=O)=O)=CC=C2N1)=O
Molecular Formula
C22H20N2O5
Molecular Weight
392.40
References & Citations
[1]Kassabri L, et al. Druglike Molecular Degraders of the Oncogenic RNA-Binding Protein HuR[J]. JACS Au, 2025.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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