CD73-IN-21
CD73-IN-21 (Compound 12f) is an Ecto-5′-nucleotidase (CD73) inhibitor with Kis of 20 and 302 nM for hCD73 and mCD73, respectively. CD73-IN-21 can be used for cancers like breast cancer research[1].
Product Specifications
UNSPSC
12352005
Target
CD73
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Smiles
O[C@@H]1[C@H](O)[C@@H](COCP([O-])(O)=O)O[C@H]1N2C=CC3=C2N=C(N=C3C4=C5C=CC=CC5=CC=C4)Cl.CC[NH+](CC)CC
Molecular Formula
C28H36ClN4O7P
Molecular Weight
607.03
References & Citations
[1]Šímová M, et al. Identification of 6-Aryl-7-Deazapurine Ribonucleoside Phosphonates as Inhibitors of Ecto-5′-Nucleotidase (CD73) [J]. ACS Pharmacology & Translational Science, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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