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CD73-IN-21

CD73-IN-21 (Compound 12f) is an Ecto-5′-nucleotidase (CD73) inhibitor with Kis of 20 and 302 nM for hCD73 and mCD73, respectively. CD73-IN-21 can be used for cancers like breast cancer research[1].

Product Specifications

UNSPSC

12352005

Target

CD73

Related Pathways

Immunology/Inflammation

Field of Research

Cancer

Smiles

O[C@@H]1[C@H](O)[C@@H](COCP([O-])(O)=O)O[C@H]1N2C=CC3=C2N=C(N=C3C4=C5C=CC=CC5=CC=C4)Cl.CC[NH+](CC)CC

Molecular Formula

C28H36ClN4O7P

Molecular Weight

607.03

References & Citations

[1]Šímová M, et al. Identification of 6-Aryl-7-Deazapurine Ribonucleoside Phosphonates as Inhibitors of Ecto-5′-Nucleotidase (CD73) [J]. ACS Pharmacology & Translational Science, 2025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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