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Carbonic anhydrase-IN-34

Carbonic anhydrase-IN-34 is a carbonic anhydrases (CAs) inhibitor (compound 9d) with IC50s of 1.01 μM against hCA-II, 0.21 μM against hCA-IX and 0.88 μM against hCA-XII. Carbonic anhydrase-IN-34 has potential applications in the research of several disorders, including epilepsy, glaucoma, obesity, and cancer[1].

Product Specifications

UNSPSC

12352005

Target

Carbonic Anhydrase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer; Metabolic Disease; Neurological Disease

Smiles

NS(=O)(C1=CC=C(C=C1)C2=CC=C(C=C2)NC3=CC=NC=C3)=O

Molecular Formula

C17H15N3O2S

Molecular Weight

325.38

References & Citations

[1]Sharif M, et al. Facile synthesis of aminobiphenyl sulfonamides via Chan-Lam coupling and their biological evaluation as potent carbonic anhydrase inhibitors. Sci Rep. 2025 Jul 15;15 (1) :25661.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CA II; CA IX; CA XII

Curated Selection

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