α-Synuclein inhibitor 15
α-Synuclein inhibitor 15 (Compound 1) is an inhibitor targeting the fibrillation growth of α-synuclein (IC50=18 μM) . α-Synuclein inhibitor 15 is promising for research of neurodegenerative diseases, such as Parkinson's disease (PD) and Lewy body dementia (LBD) [1].
Product Specifications
CAS Number
[414880-30-1]
UNSPSC
12352005
Target
α-synuclein
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
O=C(C1CCN(CC2=CC(OC)=C(O)C(OC)=C2)CC1)OCC
Molecular Formula
C17H25NO5
Molecular Weight
323.38
References & Citations
[1]Hwang H, et al. Identification of Small Molecule Dimethyoxyphenyl Piperazine Inhibitors of Alpha-Synuclein Fibril Growth. bioRxiv [Preprint]. 2025 Jun 29:2025.06.26.661821.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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