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α-Synuclein inhibitor 15

α-Synuclein inhibitor 15 (Compound 1) is an inhibitor targeting the fibrillation growth of α-synuclein (IC50=18 μM) . α-Synuclein inhibitor 15 is promising for research of neurodegenerative diseases, such as Parkinson's disease (PD) and Lewy body dementia (LBD) [1].

Product Specifications

CAS Number

414880-30-1

UNSPSC

12352005

Target

α-synuclein

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Smiles

O=C(C1CCN(CC2=CC(OC)=C(O)C(OC)=C2)CC1)OCC

Molecular Formula

C17H25NO5

Molecular Weight

323.38

References & Citations

[1]Hwang H, et al. Identification of Small Molecule Dimethyoxyphenyl Piperazine Inhibitors of Alpha-Synuclein Fibril Growth. bioRxiv [Preprint]. 2025 Jun 29:2025.06.26.661821.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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