α5β1 integrin agonist-2
α5β1 integrin agonist-2 (Compound 2) is a highly selective α5β1 integrin agonist (EC50=45.98 nM) . α5β1 integrin agonist-2 enhances extracellular matrix adhesion and Akt/ERK signaling activation. α5β1 integrin agonist-2 is promising for research of ischemic stroke[1].
Product Specifications
UNSPSC
12352005
Target
Akt; ERK; Integrin
Related Pathways
Cytoskeleton; MAPK/ERK Pathway; PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Purity
99.80
Smiles
O=C(O)CC(C1)N(C(NC2=CC(F)=CC=C2C)=O)C1=O
Molecular Formula
C13H13FN2O4
Molecular Weight
280.25
References & Citations
[1]Giraldi V, et al. Targeting α4β1 integrin: from cyclic to linear ligands, effects of chemical modifications. Eur J Med Chem. 2025 Nov 5;297:117965.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α5β1
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Mouse MICAL-Like Protein 1 (MICALL1) ELISA Kit
Mouse MICAL-Like Protein 1 (MICALL1) ELISA Kit
Mouse MICAL-Like Protein 1 (MICALL1) ELISA Kit