CHIKV nsP2 protease-IN-3
CHIKV nsP2 protease-IN-3 (Compound 5) is an irreversible covalent inhibitor targeting the nonstructural protein 2 (nsP2) cysteine protease of chikungunya virus (CHIKV) (IC50=0.5 μM) . CHIKV nsP2 protease-IN-3 inhibits viral RNA replication. CHIKV nsP2 protease-IN-3 is promising for research of alphaviruses[1].
Product Specifications
UNSPSC
12352005
Target
Virus Protease
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=S(OCC(NC1=NNC(C2=CC=CC=C2OCC)=C1)=O)(NC)=O
Molecular Formula
C14H18N4O5S
Molecular Weight
354.38
References & Citations
[1]Ghosal A, et al. N-Alkyl Sulfamates as a New Class of nsP2 Cysteine Protease Inhibitors with Broad Spectrum Antialphaviral Activity[J]. bioRxiv, 2025: 2025.06. 30.662352.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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