JNK-IN-24
JNK-IN-24, a JNK inhibitor, is an anti-metastatic cancer agent. JNK-IN-24 downregulates JNK and MMP1 expression in Scrib knockdown induced cancer tissues. JNK-IN-24 promotes recovery from tumorous wing disc phenotype of ScribRNAi. JNK-IN-24 can be used for the study in various epithelial cell-derived cancers[1].
Product Specifications
CAS Number
[2226808-28-0]
UNSPSC
12352005
Target
JNK; MMP
Related Pathways
MAPK/ERK Pathway; Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C(C1=C(C)OC2=C(C(O)=CC(O)=C2)C1C3=CC=C(Cl)C=C3)OCC
Molecular Formula
C19H17ClO5
Molecular Weight
360.79
References & Citations
[1]Raghuvanshi V, et al. Anti-metastatic cancer potential of 4H-chromene derivatives targeting JNK in Scribble knockdown induced epithelial cancer model: In vivo and in silico studies. Bioorg Chem. 2025 Aug;163:108741.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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